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万种鸟类基因组打算第二阶段钻研功效颁发

2020-11-17 昆明植物钻研所
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yuyinbobao

  11月12日,中国迷信院昆明植物钻研所钻研员张国捷及其团队,连系深圳华大性命迷信钻研院、丹麦哥本哈根大学等多家单元,在Nature上以封面情势同期颁发了两篇文章,报道了万种鸟类基因组打算第二阶段(科级别)的钻研功效。该钻研团队颁发了363种鸟类基因组数据,同时经由进程这一数据成立了无参考序列下多基因组比对和阐发的新方式,并基于这一新方式说明高密度物种取样对生物多样性钻研的首要性。

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  无参的全基因组比对数据集为周全剖析鸟类遗传多样性特点的演变进程和份子遗传机制供给了全新的切入点。在另一篇论文中,该钻研团队借助这一算法的上风成立了加倍完美的同源基因调集,并开辟了一套判定肆意演变分支特异取得和丧失序列的方式,从而完全描画出鸟类物种谱系基因组静态演变图谱。钻研发明,这些静态变更的基因组地区常常存在一些分支特异基因或调控元件,能够或许与物种特同性状的发源和演变有关。比方,雀形目鸟类基因组多出一个发展激素基因的拷贝。雀形目中的鸣禽丧失了Cornulin基因,该基因所编码的卵白首要位于食管和口腔上皮细胞,其缺失能够或许会引发食管上皮的粘弹性特点发生变更,进而使得食管上部直径能够或许发生疾速变更来调剂的声道,这能够或许与其多样化的纯音发声演变有关。

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